Isco is reportedly keen on leaving Real Madrid in January in order to improve his chances of getting picked by Spain for Euro 2020.
The Spaniard has endured a tough beginning to the current season with Los Blancos and he has played only 285 minutes of first-team football.
With the lack of impact, he has fallen out-of-favour with La Roja as well and a call-up appears unlikely unless he can impress at the club level.
According to Marca, the former Malaga man wants to leave Los Blancos at the turn of the year with his national team spot at stake.
Isco has contributed 51 goals and 54 assists from 314 appearances for Los Blancos across all competitions.
The 28-year-old will want the assurance of regular playing time whomever he joins during the winter transfer window.
He could be available for just £18m with his contract expiring in June 2021.